Elasticity of microenvironment and cancer metastasis - Taher Saif, University of Illinois at Urbana-Champaign from 3gpa Watch Video
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Description: Cancer deaths are mostly caused by metastasis of malignant cells, not by the tumor itself. During nmetastasis, cancer cells turn off adhesion ability, de-adhere from their neighbors or the extracellular nmatrix (ECM), enter the lymphatic system or the blood stream as suspensions, invade new host tissues, nregain adhesive activity and form new colonies. Thus, cell adhesion plays a central role in metastasis. nHere we show, for the first time, that mechanical stiffness of cancer cells’ microenvi
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